Wannan shafin yanar gizon yana amfani da kukis domin mu iya ba ku damar kwarewa mafi kyau. Ana adana bayanin kuki a cikin burauzarka kuma yana aiki da ayyuka kamar gane da ku idan kun dawo zuwa shafin yanar gizon mu da kuma taimaka wa tawagar mu fahimci wane ɓangaren shafin yanar gizon da kuka samu mafi ban sha'awa da amfani.
McLean 12 (2019)
Rukunin bayanan EBS Genotyping, wanda DEBRA UK da MRC suka bayar, sun tattara bayanai kan jerin kwayoyin halittar marasa lafiya na Burtaniya KRT14. Yana nufin gano maye gurbi da ke haifar da epidermolysis bullosa simplex, yana ba da izinin ƙirar warkewa da aka yi niyya. Manufar ita ce fahimtar canje-canjen kwayoyin halitta don haɓaka madaidaicin jiyya ga EBS ta hanyar mai da hankali kan murkushe ƙwayoyin cuta.
Game da kudaden mu
| Jagoran Bincike | Farfesa Irwin McLean da Dr Robyn Hickerson |
| Institution | Cibiyar Nazarin cututtukan fata da Magungunan Halittu (DGEM), Jami'ar Dundee |
| Nau'in EB | EBS |
| Hanyar haƙuri | N / A |
| Adadin kuɗi | £24,000 (haɓakar babban tallafi daga Majalisar Binciken Kiwon Lafiya (MRC) ko £1.81m sama da shekaru 5) |
| Tsawon aikin | 5 shekaru |
Bayanan aikin
Rubutun bayanan epidermolysis bullosa simplex (EBS) Genotyping wani shiri ne wanda DEBRA UK da Majalisar Binciken Kiwon Lafiya (MRC) suka kafa don tattara bayanai kan nau'ikan nau'ikan marasa lafiya na EBS a cikin Burtaniya. Manufar wannan aikin shine don ƙayyade jerin DNA na keratin 14 (Saukewa: KRT14) Halin da aka shafa a cikin marasa lafiya na EBS da ke cikin Burtaniya don tsara takamaiman hanyoyin warkewa.
Kowa yana da kwafi biyu na Saukewa: KRT14 kwayoyin halitta – kwafin uba daya da kwafin uwa daya. Duk da haka, a cikin marasa lafiya na EBS, kwayar halitta ɗaya ce ta al'ada kuma tana yin furotin keratin na yau da kullum amma ɗayan yana da 'kuskure' wanda ya hana sakamakon da keratin keratin da ke haifar da shi daga aiki yadda ya kamata kuma mafi mahimmanci yana tsoma baki tare da aikin keratin na yau da kullum, yana sa fata ta zama mai rauni. Ta hanyar kashe ƙwayar cuta mara kyau, furotin keratin na yau da kullun na iya aiki yadda ya kamata ba tare da tsangwama ba.
Ƙungiyar ta jera DNA don gano ko akwai wasu canje-canje a cikin Saukewa: KRT14 gene code. Dalilin yin haka shine don gina hoton duk canje-canje a cikin Saukewa: KRT14 kwayoyin halitta a cikin marasa lafiya na EBS, ba kawai maye gurbin da ke haifar da alamun cutar ba. Ta hanyar tattara wannan bayanin daga yawancin majinyatan EBS da mutanen da ba su da EBS, ana fatan wannan zai taimaka wajen ƙirƙira ingantattun jiyya ga majinyatan EBS a nan gaba.
Ana amfani da bayanai daga wannan aikin don sanar da aikin zuwa wani sabon salon jiyya wanda ƙungiyar ɗaya ke haɓakawa. Ana iya samun ƙarin akan wannan aikin akan shafin yanar gizon aikin.