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Ayyukan bincike na EB

DEBRA UK ita ce mafi girman masu ba da tallafin Burtaniya Binciken EB, bayar da kyauta ga masu bincike tare da gwaninta a fannin kimiyya da likitanci mafi dacewa ga iyalai da ke zaune tare da EB.

Fayil ɗinmu na ayyukan bincike ya haɗa da aikin dakin gwaje-gwaje na asali, bincike kan hanyoyin maganin ƙwayoyin cuta da ƙwayoyin cuta da sake dawo da ƙwayoyi, da kuma ayyukan da ke haifar da canji a cikin alamun taimako don warkar da rauni da kuma maganin ciwon daji.

Binciken da muke ba da kuɗi ajin duniya ne, kuma hakan ya faru ne saboda ba wai kawai muna tallafawa masana kimiyya da likitocin Burtaniya ba amma mafi kyawun duniya. Yawancin ayyukan da muke bayarwa sun haɗu da ilimi da fasaha daga masu bincike a wuraren bincike da yawa a cikin Burtaniya da na duniya.

Mutane biyu da suka tsunduma cikin ayyukan bincike suna nunawa a kwamfutar hannu da ke nuna jerin haruffan DNA cikin shuɗi da rawaya. Mutum daya yana sanye da rigar lab.

Tsarin kwayoyin halittar EBS

Dr Laura Valinotto, CEDIGEA, Jami'ar Buenos Aires, Argentina
Ya koyi
Hoton da ba a iya gani ba yana nuna ƙwayoyin cuta mai siffar shuɗi a kan wani koren rubutu mai laushi.

Biofilms sun jinkirta warkar da rauni na EB

Dr Josefine Hirschfeld, Jami'ar Birmingham, Birtaniya
Ya koyi
Misalin madaidaicin DNA yana mu'amala tare da saman graphene mai siffar hexagonal, yana nuna ma'amalar kwayoyin halitta akan bangon grid.

Sauƙaƙe gwajin kwayoyin halitta don kowane nau'in EB

Dr Ene-Choo Tan, KK Womens and Children Hospital, Singapore
Ya koyi
Misalin igiyoyin DNA guda biyu tare da ƙarewa masu haske a kan bango mai duhu tare da raƙuman gears da ƙirar kewaye.

CRISPR/Cas9 don gyara halittar RDEB

Dr Sergio López-Manzaneda, CIEMAT, Spain
Ya koyi
Misalin kwayar cutar da ke shigar da kwayoyin halitta a cikin tantanin halitta, yana nuna kwayar cutar kwayar cutar da ke hadewa da kuma tura DNA ko RNA cikin kwayar halitta.

Inganta isar da jiyya na RDEB

Dr Ángeles Mencía, CIEMAT, Spain
Ya koyi
Bayanin gefen kusa na jaririn da ke kwance, yana kallon sama, tare da mai da hankali kan ido da dogayen gashin ido.

Rage tabon ido na DEB/JEB

Farfesa Keith Martin, CERA, Jami'ar Melbourne, Australia
Ya koyi
Hoton zane mai ban dariya na igiyar DNA

Hickerson 2 (2019)

Dr Robyn Hickerson, Jami'ar Dundee, Birtaniya
Ya koyi
Hoton zane mai ban dariya na igiyar DNA

Hubbard 1 (2017)

Lynne Hubbard, Asibitin St Thomas, London, UK
Ya koyi
Hoton zane mai ban dariya na igiyar DNA

Liossi (2014)

Dr Christina Liossi, Jami'ar Southampton, UK
Ya koyi
Wani mai bincike sanye da safar hannu shuɗi ya sanya abincin Petri a ƙarƙashin na'urar hangen nesa don dubawa.

PhD: rage blisters a cikin JEB

Dr Emma Chambers, QMUL, Birtaniya
Ya koyi
Mutumin da ke sanye da safofin hannu shuɗi yana amfani da pipette don canja wurin jan ruwa zuwa faranti mai rijiyoyi da yawa, tare da kayan aikin lab da kwantena a bango.

PhD: inganta gyaran fata a cikin JEB

Dr Emanuel Rognoni, QMUL, Birtaniya
Ya koyi
Misalin madaidaicin DNA da ke mu'amala da koren kwayoyin halitta mai siffar zobe, wanda aka saita akan bangon gradient.

PhD: nazarin raunin nanoneedle a RDEB

Farfesa John McGrath, KCL, Birtaniya
Ya koyi
Hoton da ke nuna matakan warkar da raunuka: gudan jini tare da samuwar scab, ninka tantanin halitta, da maido da nama tare da samar da jini. Alamun sun haɗa da epidermis, dermis, fibroblast, da macrophage.

PhD: warkar da rauni a kowane nau'in EB (2024)

Farfesa Adrian Heagerty da Dr Ajoy Bardhan, Jami'ar Birmingham, Birtaniya
Ya koyi
Hoton wani yanki na fata na ɗan adam, tare da yadudduka da ake iya gani, ɓangarorin gashi, tasoshin jini, da wani wuri mai haske da ke kewaye da rauni.

PhD: haɓaka YAP/TAZ don hanzarta warkar da rauni

Dr Gernot Walko, QMUL, Birtaniya
Ya koyi
Hoton mutum rike da kwamfutar hannu a hannunsu.

An sake yin amfani da allunan Psoriasis don EBS

Dr Christine Chiaverini, Cibiyar Asibitin Jami'ar De Nice, Faransa
Ya koyi
Littafin rubutu, m bayanin kula, da kwamfutar tafi-da-gidanka suna zaune kusa da takardar da ke nuna zane-zane masu launi da hotuna akan tebur.

Rayuwa tare da EB a Burtaniya

Dokta Zoe Venables, Jami'ar Gabashin Anglia, Birtaniya
Ya koyi
Yaro mai murmushi sanye da fukafukan malam buɗe ido shuɗi yana riƙe da yankan tsintsiya mai launin ruwan hoda a gaban ƙofar turquoise.

Yin maganin JEB tare da furotin laminin

Dr Matthew Caley, QMUL, Birtaniya
Ya koyi
Yaro da wasa yana amfani da cokali don duba bakin babba. Dukansu suna cikin gida, suna zaune akan kujera.

DEB ciwon daji da kuma bakin rauni warkar

Dr Inês Sequeira, QMUL, Birtaniya
Ya koyi
Maɓallan madannai guda biyar masu rubutun "PASTE" an tsara su akan bangon ja.

Jiyya na dindindin na DEB

Dokta Joanna Jacków, KCL, Birtaniya
Ya koyi
Likitan harhada magunguna yana nazarin kwalaben magani a kan faifan da ke cike da kayayyakin magunguna daban-daban.

Maimaita statins don RDEB kansar fata

Dr Roland Zauner, EB House, Austria
Ya koyi
Murmushin dangi a kyamara. Wani yaro yana sanye da rigar DEBRA purple

Kayan aikin jin daɗi ga duk iyayen EB

Farfesa Andrew Thompson, Jami'ar Cardiff, UK
Ya koyi
Kusa da ƙafafu na jariri yana hutawa a hannun manya tare da ƙusoshi masu launin baki, wanda aka saita akan bango mai laushi, mai duhu.

Ingantacciyar maganin blister don EBS

Farfesa John Connelly, QMUL, Birtaniya
Ya koyi
Kusa da ido mai launin ruwan iris, dogayen gashin ido, da kuma nuna haske akan almajiri.

Faɗin ido ga kowane nau'in EB

Farfesa Liam Grover, Jami'ar Birmingham, Birtaniya
Ya koyi
Mutumin da yake riƙe da farantin rijiyar 96 bayyananne mai ɗauke da ruwa kala-kala daban-daban a cikin ɗakin gwaje-gwaje.

Magungunan tantancewa don kai hari kan kansar RDEB

Farfesa Gareth Inman, Cibiyar CRUK Scotland, Birtaniya
Ya koyi
Hoton da ke nuna wani yunƙuri na haƙuri don bincika magunguna na tushen cannabinoid don ciwo da ƙaiƙayi a cikin EB, wanda ke nuna kwakwalwa, fata, da ganyen cannabis tare da ƙoƙarin PhD da aka mayar da hankali kan inganta gyaran fata a cikin JEB.

Maganin Cannabinoid don duk EB zafi da ƙaiƙayi

Farfesa Dr André Wolff da Dr Marieke Bolling, Cibiyar Kiwon Lafiya ta Jami'ar Groningen, Netherlands
Ya koyi
Misalin mutum mai kunar rana a bayansa, yana tsaye a ƙarƙashin hasken rana. Fatar jiki tana nuna sifofi hexagonal, suna jaddada fitowar rana da tasirin zafi.

KEB da kansar fata (2024)

Farfesa Valerie Brunton, Jami'ar Edinburgh, Birtaniya
Ya koyi

Mayar da magungunan rigakafin tabo a cikin RDEB (2023)

Dr Daniele Castiglia, Istituto Dermopatico dell'Immacolata, IRCCS, Italiya
Ya koyi
Misali na wani mutum da ke da wani wuri mai ban sha'awa yana nuna ƙwayar ƙwayar ƙwayar ƙwayar cuta a goshinsa da kuma kusa da ciwon fata.

RDEB ciwon fata (2023)

Farfesa Gareth Inman, Jami'ar Glasgow, Birtaniya
Ya koyi

Tabo a cikin RDEB (2023)

Farfesa Giovanna Zambruno, Bambino Gesù Children's Hospital (IRCCS), Rome, Italiya
Ya koyi

Fahimtar cututtukan iska a cikin JEB (2023)

Dr Colin Butler, GOSH, UK
Ya koyi

Shigar da tsarin rigakafi a cikin RDEB (2023)

Dr Yanling Liao, NYMC, Amurka
Ya koyi

Skin microbiome na kowane nau'in EB (2023)

Farfesa Iain Chapple, Birmingham Dental School and Hospital, UK
Ya koyi

Fesa akan jigon halittar RDEB (2022)

Dr Su Lwin, KCL, UK
Ya koyi

Nazarin Alamun PEBLES RDEB (2022)

Farfesa Jemima Mellerio, St John's Institute of Dermatology and GOSH, London
Ya koyi

Tafiya tare da EBS (2022)

Dokta Deborah Falla da Farfesa Adrian Heagerty, Jami'ar Birmingham, Birtaniya
Ya koyi

Maganin fesa baki/maƙogwaro (2022)

Farfesa Liam Grover, Jami'ar Birmingham, Birtaniya
Ya koyi

Rigosertib don RDEB SSC (2022)

Dr Andrew South, Jami'ar Thomas Jefferson, Amurka
Ya koyi

Kwayoyin tsarin rigakafi da RDEB raunuka (2022)

Farfesa Dr Sabine Ememing, Asibitin Jami'ar Cologne, Jamus
Ya koyi

Yin maganin ƙaiƙayi na DEB tare da ƙananan ƙwayoyin cuta (2022)

Farfesa John McGrath da Farfesa Jemima Mellero, KCL, Birtaniya
Ya koyi

Maganin Halitta don EBS da RDEB (2022)

Dokta Robyn Hickerson da Dr Peter van den Akker, Jami'ar Dundee, Birtaniya
Ya koyi

Decorin gel don rage tabo (2019)

Dr Mark de Souza da Farfesa Jean Tang, FIBRX Derm Inc, Amurka
Ya koyi

LENTICOL F (2019)

Farfesa John McGrath, St John's Institute of Dermatology and Institute of Child Health, UK
Ya koyi

Inman-South 1 (2019)

Dr Gareth Inman da Dr Andrew South, Jami'ar Dundee, UK
Ya koyi

Hickerson 1 (2019)

Dr Robyn Hickerson, Jami'ar Dundee, Birtaniya
Ya koyi

McLean 12 (2019)

Farfesa Irwin McLean da Dr Robyn Hickerson, Jami'ar Dundee, Birtaniya
Ya koyi

Brunton 1 (2018)

Farfesa Valerie Brunton, Jami'ar Edinburgh, Birtaniya
Ya koyi

ADSTEM (2018)

Farfesa John McGrath, St John's Institute of Dermatology, UK
Ya koyi

Roopenian 2 (2017)

Dr Derry Roopenian, The Jackson Laboratory, Amurka
Ya koyi

Laraba 3 (2017)

Farfesa Jakub Tolar, Jami'ar Minnesota, Amurka
Ya koyi

Gaggioli 2 (2017)

Dr Cedric Gaggioli, ADSM, Nice, Faransa
Ya koyi

Bauer 5 (2017)

Farfesa Johann Bauer, EB House, Austria
Ya koyi

Lahadi 1 (2017)

Farfesa Jouni Uitto, Jami'ar Thomas Jefferson, Amurka
Ya koyi

O'Toole (2015)

Farfesa Edel O'Toole, QMUL, Birtaniya
Ya koyi

EBSTEM (2015)

Farfesa John McGrath, St John's Institute of Dermatology, UK
Ya koyi

Laraba 2 (2015)

Farfesa Jakub Tolar, Jami'ar Minnesota, Amurka
Ya koyi

McLean/Heagerty 1 (2014)

Farfesa Irwin Mclean da Farfesa Adrian Heagerty, Jami'ar Dundee, Birtaniya
Ya koyi

McGrath (2014)

Farfesa John McGrath, Asibitin Guy London, UK
Ya koyi

Sonnenberg (2013)

Dr Arnoud Sonnenberg, Cibiyar Ciwon daji ta Netherlands, Netherlands
Ya koyi

Kudu (2013)

Dr Andrew South, Jami'ar Thomas Jefferson, Amurka
Ya koyi
Gine-gine na zamani, mai hawa da yawa tare da facade na gilashi da alamar karanta "Ginin Binciken Ciwon daji." Akwai filin ciyawa a gaba da ƴan mutane kusa da ƙofar.

Abokin Hulɗa: RDEB samfuran kansar pre-asibiti

Farfesa Gareth Inman, Cibiyar CRUK Scotland, Birtaniya
Ya koyi
Fare mai shuɗi tare da "NHS" a cikin fararen haruffa, an sanya shi akan bangon shuɗi mai duhu.

Haɗin gwiwar NHS England: Fahimtar bayanan mara lafiyar EB da aka gudanar a cikin NHS

Dr Zoe Venables da Marta Kwiatkowska, NHS Ingila, Birtaniya
Ya koyi